Chiral Nonracemic Pyridine Thiols and Thioethers Applied in Palladium-Catalyzed Allylic Substitution. An Example of Near-Perfect Enantioselection

Journal of Organic Chemistry

Volumn 63, Issue 16, 1998, Pages 5533-5540

  Koning, B ^a   Meetsma, A ^a   Kellogg, R M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000253117     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9806299     Document Type: Article

References (42)

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33. The one-step one-pot approach involves double deprotonation with 2.2 equiv of n-BuLi followed by 2 equiv of thioketone. In the two-step one-pot approach, the monocondensation product is not isolated, and a second equivalent of n-BuLi and thioketone are added after the monoadduct has been formed.
34. Determined on a 20% permethylated β-cyclodextrin column; length 30 m.
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41. Crystallographic data (excluding, structure factors) for the structures reported in this paper have been deposited with the Cambridge Crystallographic Data Centre. Deposition numbers are 101825, 101829, and 101830. Copies of the data can be obtained free of charge on application to the Director, CCDC, 12 Union Road, Cambridge CB2 IEZ, UK (Fax: int code +(1223)336-033, E-mail: teched@chemcrys.cam.ac.uk).
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