Human rabies: A disease of complex neuropathogenetic mechanisms and diagnostic challenges

Lancet Neurology

Volumn 1, Issue 2, 2002, Pages 101-109

  Hemachudha, Thiravat ^a   Laothamatas, Jiraporn ^b   Rupprecht, Charles E ^c  

^a KING CHULALONGKORN MEMORIAL HOSPITAL   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUID; CENTRAL NERVOUS SYSTEM INFECTION; CLINICAL FEATURE; COMA; DIAGNOSTIC TEST; GUILLAIN BARRE SYNDROME; HEALTH CARE PERSONNEL; HUMAN; INCUBATION TIME; MOLECULAR MECHANICS; NEUROPATHOLOGY; PARALYSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROPHYLAXIS; RABIES; RABIES VIRUS; REVIEW; RNA VIRUS; VIRUS DETECTION; VIRUS TRANSMISSION; WORLD HEALTH ORGANIZATION; ANIMAL; BRAIN; DOG; PATHOLOGY;

ANIMALS; BRAIN; DOGS; HUMANS; RABIES;

EID: 0000249124     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(02)00041-8     Document Type: Review

References (86)

1. World Health Organization. Strategies for the control and elimination of rabies in Asia. Geneva: WHO, 2001.
2. World Health Organization. World survey of rabies number 34 (for the year 1998). Geneva: WHO, 2000. http://www.who.int/emc/diseases/zoo/wsr98/HTML_version/wsr98index.html , accessed May 2002.
3. World Health Organization. Rabies control in Asia. Proceedings of the fourth international symposium organised by the Merieux foundation and WHO. Paris: John Libbey Eurotext, 2001.
4. Rupprecht C.E., Hanlon C.A., Hemachudha T. Rabies re-examined. Lancet Infect Dis. 2:2002;337-353.
5. Noah D.L., Drenzek C.L., Smith J.S., et al. Epidemiology of human rabies in the United States, 1980 to 1996. Ann Intern Med. 128:1998;922-930.
6. Centers for Disease Control And Prevention. Epidemiology of human rabies. http://www.cdc.gov/ncidod/dvrd/rabies, accessed May 2002.
7. Hanna J.N., Carney I.K., Smith G.A., et al. Australian bat lyssavirus infection: a second human case, with a long incubation period. Med J Aust. 172:2000;597-599.
8. Fraser GC, Hooper PT, Lunt RA, et al. Encephalitis caused by a Lyssavirus in fruit bats in Australia. Emerg Infect Dis 1996; 2: 327-31. http://www.cdc.gov/ncidod/EID/index.htm , accessed May 2002.
9. Hemachudha T. Rabies. Vinken P.J., Bruyn G.W., Klawans H.L. Handbook of clinical neurology, revised series. 1989;383-404 Elsevier Science Publishers, Amsterdam.
10. Sitthi-Amorn C., Jiratanavattana V., Keoyoo J., Sonpunya N. The diagnostic properties of laboratory tests for rabies. Int J Epidemiol. 16:1987;602-605.
11. Morimoto K., Patel M., Corisdeo S., et al. Characterization of a unique variant of bat rabies virus responsible for newly emerging human cases in North America. Proc Natl Acad Sci USA. 93:1996;5653-5658.
12. Hemachudha T., Phuapradit P. Rabies. Curr Opin Neurol. 10:1997;260-267.
13. Hemachudha T. Human rabies: clinical aspects, pathogenesis and potential therapy. Curr Top Microbiol Immunol. 187:1994;121-143.
14. Hemachudha T., Phanuphak P., Sriwanthana B., et al. Immunologic study of human encephalitic and paralytic rabies: preliminary report of 16 patients. Am J Med. 84:1988;673-677.
15. Hemachudha T., Mitrabhakdi E. Rabies. Davis L.E., Kennedy P.G.E. Infectious diseases of the nervous system. 2000;401-444 Butterworth-Heinemann, Oxford.
16. Smith J.S., Fishbein D.B., Rupprecht C.E., Clark K. Unexplained rabies in three immigrants in the United States: a virologic investigation. N Engl J Med. 324:1991;205-211.
17. Hemachudha T., Chutivongse S., Wilde H. Latent rabies. N Engl J Med. 324:1991;1890-1891.
18. Huang C.C., Liu C.C., Chang Y.C., Chen C.Y., Wang S.T., Ye T.F. Neurologic complications in children with enterovirus 71 infection. N Engl J Med. 341:1999;936-942.
19. Solomon T., Dung N.M., Kneen R., Gainsborough M., Vaughn D.W., Khanh V.T. Japanese encephalitis. J Neurol Neurosurg Psychiatry. 68:2000;405-415.
20. Goh K.J., Tan C.T., Chew N.K., et al. Clinical features of Nipah virus encephalitis among pig farmers in Malaysia. N Engl J Med. 342:2000;1229-1235.
21. Hemachudha T., Tirawatnpong S., Phanthumchinda K. Seizures as the initial manifestation of paralytic rabies. J Neurol Neurosurg Psychiatry. 52:1989;808-810.
22. Tirawatnpong S., Hemachudha T., Manutsathit S., Shuangshoti S., Phanthumchinda K., Phanuphak P. Regional distribution of rabies viral antigen in central nervous system of human encephalitic and paralytic rabies. J Neurol Sci. 92:1989;91-99.
23. Phuapradit P., Manatsathit S., Warrell M.J., Warrell D.A. Paralytic rabies: some unusual clinical presentations. J Med Assoc Thai. 68:1985;106-110.
24. Hemachudha T., Phanthumchinda K., Phanuphak P., Manutsathit S. Myoedema as a clinical sign in paralytic rabies. Lancet. 1:1987;1210.
25. Pleasure S.J., Fischbein N.J. Correlation of clinical and neuroimaging findings in a case of rabies encephalitis. Arch Neurol. 57:2000;1765-1769.
26. Brass D.A. Rabies in bats: natural history and public health implications. 1994;Livia Press, Connecticut.
27. Nelson D.A., Berry R.G. Fatal rabies associated with extensive demyelination. Arch Neurol. 50:1993;317-323.
28. Allworth A., Murray K., Morgan J. A human case of encephalitis due to a lyssavirus recently identified in fruit bats. Commun Dis Intell. 20:1996;504.
29. Metze K., Feiden W. Rabies virus ribonucleoprotein in the heart. N Engl J Med. 324:1991;1814-1815.
30. Kureishi A., Xu L.Z., Wu H., Stiver H.G. Rabies in China: recommendations for control. Bull World Health Organ. 70:1992;443-450.
31. Hattwick M.A., Weiss T.T., Stechschulte C.J., Baer G.M., Gregg M.B. Recovery from rabies: a case report. Ann Intern Med. 76:1972;931-942.
32. Porras C., Barboza J.J., Fuenzalida E., Adaros H.L., Oviedo A.M., Furst J. Recovery from rabies in man. Ann Intern Med. 85:1976;44-48.
33. Rabies in a laboratory worker. MMWR Morb Mortal Wkly Rep. 26:1977;183-184.
34. Alvarez L, Cashat M, Arellano E, Baer GM. A new phenomenon in rabies: partial recovery in children treated prompty with potent vaccine. In: Proceedings of the 7th international meeting on advances towards rabies control in the Americas. CDC, Atlanta, GA, USA, 1996, 78.
35. Baer G.M., Shaddock J.H., Quirion R., Dam T.V., Lentz T.L. Rabies susceptibility and acetylcholine receptor. Lancet. 335:1990;664-665.
36. Hattwick M.A.W. Human rabies. Public Health Rev. 3:1974;229-274.
37. Debbie J.G., Trimarchi C.V. Prophylaxis for suspected exposure to bat rabies. Lancet. 350:1997;1790-1791.
38. Hattwick M.A.W., Gregg M.B. The disease in man. Baer G.M. The natural history of rabies. 1975;281-303 Academic Press, New York.
39. Constantine DG. Rabies transmission by air in bat caves. US Public Health Service publication 1967.
40. Tariq W.U., Shafi M.S., Jamal S., Ahmad M. Rabies in man handling infected calf. Lancet. 337:1991;1224.
41. Fishbein D.B., Robinson L.E. Rabies. N Engl J Med. 329:1993;1632-1638.
42. Helmick C.G., Tauxe R.V., Vernon A.A. Is there a risk to contacts of patients with rabies? Rev Infect Dis. 9:1987;511-518.
43. Crepin P., Audry L., Rotivel Y., Gacoin A., Caroff C., Bourhy H. Intravitam diagnosis of human rabies by PCR using saliva and cerebrospinal fluid. J Clin Microbiol. 36:1998;1117-1121.
44. Lumbiganon P., Wasi C. Survival after rabies immunisation in newborn infant of affected mother. Lancet. 336:1990;319.
45. Charlton K.M. The pathogenesis of rabies and other lyssaviral infections: recent studies. Curr Top Microbiol Immunol. 187:1994;95-119.
46. Lentz T.L., Wilson P.T., Hawrot E., Speicher D.W. Amino acid sequence similarity between rabies virus glycoprotein and snake venom curaremimetic neurotoxins. Science. 226:1984;847-848.
47. Hanham C.A., Zhao F., Tignor G.H. Evidence from the anti-idiotypic network that the acetylcholine receptor is a rabies virus receptor. J Virol. 67:1993;530-542.
48. Lewis P., Fu Y., Lentz T.L. Rabies virus entry at the neuromuscular junction in nerve-muscle cocultures. Muscle Nerve. 23:2000;720-730.
49. Charlton K.M., Nadin-Davis S., Casey G.A., Wandeler A.I. The long incubation period in rabies: delayed progression of infection in muscle at the site of exposure. Acta Neuropathol (Berl). 94:1997;73-77.
50. World Health Organization. 8th report of the WHO expert committee on rabies. Technical report series, no 824. Geneva: WHO, 1992.
51. Tsiang H. Interaction of rabies virus and host cells. Campbell J.B., Charlton K.M. Rabies. 1988;67-100 Kluwer Academic Publishers, Boston.
52. Tsiang H. Pathophysiology of rabies virus infection of the nervous system. Adv Virus Res. 42:1993;375-412.
53. Tangchai P., Vejjajiva A. Pathology of the peripheral nervous system in human rabies: a study of nine autopsy cases. Brain. 94:1971;299-306.
54. Minguetti G., Hofmeister R.M., Hayashi Y., Montano J.A. Ultrastructure of cranial nerves of rats inoculated with rabies virus. Arq Neuropsiquiatr. 55:1997;680-686.
55. Kucera P., Dolivo M., Coulon P., Flamand A. Pathways of the early propagation of virulent and avirulent rabies strains from the eye to the brain. J Virol. 55:1985;158-162.
56. Coulon P., Derbin C., Kucera P., Lafay F., Prehaud C., Flamand A. Invasion of the peripheral nervous systems of adult mice by the CVS strain of rabies virus and its avirulent derivative AvO1. J Virol. 63:1989;3550-3554.
57. Shankar V., Dietzschold B., Koprowski H. Direct entry of rabies virus into the central nervous system without prior local replication. J Virol. 65:1991;2736-2738.
58. Lentz T.L., Chester J. Synaptic vesicle recycling at the neuromuscular junction in the presence of a presynaptic membrane marker. Neuroscience. 7:1982;9-20.
59. Cameile P. D.E., Takei K. Molecular mechanisms in synaptic reside endocytosis and recycling. Neuron. 16:1996;481-486.
60. Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A. Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus. EMBO J. 17:1998;7250-7259.
61. Thoulouze M.I., Lafage M., Schachner M., Hartmann U., Cremer H., Lafon M. The neural cell adhesion molecule is a receptor for rabies virus. J Virol. 72:1998;7181-7190.
62. Etessami R., Conzelmann K.K., Fadai-Ghotbi B., Natelson B., Tsiang H., Ceccaldi P.E. Spread and pathogenic characteristics of a G-deficient rabies virus recombinant: an in vitro and in vivo study. J Gen Virol. 81:2000;2147-2153.
63. Kelly R.M., Strick P.L. Rabies as a transneuronal tracer of circuits in the central nervous system. J Neurosci Methods. 103:2000;63-71.
64. Raux H., Flamand A., Blondel D. Interaction of the rabies virus P protein with the LC8 dynein light chain. J Virol. 74:2000;10212-10216.
65. Jacob Y., Badrane H., Ceccaldi P.E., Tordo N. Cytoplasmic dynein LC8 interacts with lyssavirus phosphoprotein. J Virol. 74:2000;10217-10222.
66. Lopez A., Miranda P., Tejada E., Fishbein D.B. Outbreak of human rabies in the Peruvian jungle. Lancet. 339:1992;408-411.
67. Warner C.K., Zaki S.R., Shieh W.J., et al. Laboratory investigation of human deaths from vampire bat rabies in Peru. Am J Trop Med Hyg. 60:1999;502-507.
68. Sheikh K.A., Jackson A.C., Ramos-Alvarez M., et al. Paralytic rabies: immune attack on nerve fibers containing axonally transported viral proteins. Neurology. 50:(suppl. 4):1998;183-184.
69. Piyasirisilp S., Schmeckpeper B.J., Chandanayingyong D., Hemachudha T., Griffin D.E. Association of HLA and T-cell receptor gene polymorphisms with Semple rabies vaccine-induced autoimmune encephalomyelitis. Ann Neurol. 45:1999;595-600.
70. Ceccaldi P.E., Marquette C., Weber P., Gourmelon P., Tsiang H. Ionizing radiation modulates the spread of an apathogenic rabies virus in mouse brain. Int J Radiat Biol. 70:1996;69-75.
71. Sugamata M., Miyazawa M., Mori S., Spangrude G.J., Ewalt L.C., Lodmell D.L. Paralysis of street rabies virus-infected mice is dependent on T lymphocytes. J Virol. 66:1992;1252-1260.
72. Weiland F., Cox J.H., Meyer S., Dahme E., Reddehase M.J. Rabies virus neuritic paralysis: immunopathogenesis of nonfatal paralytic rabies. J Virol. 66:1992;5096-5099.
73. Camelo S., Lafage M., Lafon M. Absence of the p55 kD TNF-alpha receptor promotes survival in rabies virus acute encephalitis. J Neurovirol. 6:2000;507-518.
74. Lafon M., Lafage M., Martinez-Arends A., et al. Evidence for a viral superantigen in humans. Nature. 358:1992;507-510.
75. Dumrongphol H., Srikiatkhachorn A., Hemachudha T., Kotchabhakdi N., Govitrapong P. Alteration of muscarinic acetylcholine receptors in rabies viral-infected dog brains. J Neurol Sci. 137:1996;1-6.
76. Dietzschold B., Morimoto K., Hooper D.C. Mechanisms of virus-induced neuronal damage and the clearance of viruses from the CNS. Curr Top Microbiol Immunol. 253:2001;145-155.
77. Li Z., Feng Z., Ye H. Rabies viral antigen in human tongues and salivary glands. J Trop Med Hyg. 98:1995;330-332.
78. Deresiewicz R.L., Thaler S.J., Hsu L., Zamani A.A. Clinical and neuroradiographic manifestations of eastern equine encephalitis. N Engl J Med. 336:1997;1867-1874.
79. Nash D., Mostashari F., Fine A., et al. The outbreak of West Nile virus infection in the New York city area in 19199. N Engl J Med. 344:2001;1807-1814.
80. Hemachudha T., Griffin D.E., Giffels J.J., Johnson R.T., Moser A.B., Phanuphak P. Myelin basic protein as an encephalitogen in encephalomyelitis and polyneuritis following rabies vaccination. N Engl J Med. 316:1987;369-374.
81. Laothamatas J., Hemachudha T., Tulayadechanont S., Mitrabhakdi E. Neuroimaging in paralytic rabies. Rama Med J. 20:1997;141-148.
82. Awasthi M., Parmar H., Patankar T., Castillo M. Imaging findings in rabies encephalitis. Am J Neuroradiol. 22:2001;677-680.
83. Kalita J., Misra U.K. Comparison of CT scan and MRI findings in the diagnosis of Japanese encephalitis. J Neurol Sci. 174:2000;3-8.
84. Kamolvarin N., Tirawatnpong T., Rattanasiwamoke R., Tirawatnpong S., Panpanich T., Hemachudha T. Diagnosis of rabies by polymerase chain reaction with nested primers. J Infect Dis. 167:1993;207-210.
85. Wacharapluesadee S., Hemachudha T. Nucleic-acid sequence based amplification in the rapid diagnosis of rabies. Lancet. 358:2001;892-893.
86. Wacharapluesadee S., Hemachudha T. Urine as a source of rabies RNA detection in the diagnosis of human rabies. Clin Infect Dis. 34:2002;874-875.