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For general reviews see: (a) Soderquist, J. A. Aldrichim. Acta 1991, 24, 15. (b) Molander, G. A. Chem. Rev. 1992, 92, 29. (c) Brandukova, N. E.; Vygodskii, Y. S.; Vinogradova, S. V. Russ. Chem. Rev. 1994, 63, 345. (d) Molander, G. A. In Organic Reactions; Paquette, L. A., Ed.; John Wiley & Sons: New York, 1994; Vol. 46, p 211. (e) Molander, G. A.; Harris, C. R. Chem. Rev. 1996, 96, 307.
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For general reviews see: (a) Soderquist, J. A. Aldrichim. Acta 1991, 24, 15. (b) Molander, G. A. Chem. Rev. 1992, 92, 29. (c) Brandukova, N. E.; Vygodskii, Y. S.; Vinogradova, S. V. Russ. Chem. Rev. 1994, 63, 345. (d) Molander, G. A. In Organic Reactions; Paquette, L. A., Ed.; John Wiley & Sons: New York, 1994; Vol. 46, p 211. (e) Molander, G. A.; Harris, C. R. Chem. Rev. 1996, 96, 307.
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Several different examples of samarium(II) iodide-promoted sequential reactions have recently been described: (a) Molander, G. A.; Kenny, C. J. Org. Chem. 1991, 56, 1439. (b) Molander, G. A.; Harris, C. R. J. Am. Chem. Soc. 1995, 117, 3705. (c) Molander, G. A.; Harris, C. R. J. Am. Chem. Soc. 1996, 118, 4059.
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RLi was used only when R = t-Bu. The reaction performed with the corresponding Grignard reagent failed
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RLi was used only when R = t-Bu. The reaction performed with the corresponding Grignard reagent failed.
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The use of less than 6 equiv of samarium(II) iodide in this process resulted in the recovery of some starting material
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The use of less than 6 equiv of samarium(II) iodide in this process resulted in the recovery of some starting material.
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