Implications of hemolin glycosylation and Ca2+-binding on homophilic and cellular interactions

European Journal of Biochemistry

Volumn 266, Issue 3, 1999, Pages 964-976

  Bettencourt, Raul ^d   Gunne, Hans ^b   Gastinel, Louis ^a,c   Steiner, Håkan ^d   Faye, Ingrid ^d  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b Astra Arcus AB   (Sweden)

^c Centre National de la Recherche Scientifique   (France)

^d NONE

Author keywords

Calcium binding; Cell adhesion molecule; Glycosylation; Hemolin; Innate immunity

Indexed keywords

CALCIUM 45; COMPLEMENTARY DNA; GLYCOPROTEIN; GLYCOSIDASE; HEMOLIN; IMMUNOGLOBULIN; RECOMBINANT PROTEIN; SIALIDASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; AUTORADIOGRAPHY; CALCIUM BINDING; CELL ADHESION; CELL INTERACTION; ENZYME ACTIVITY; GLYCOSYLATION; HEMOLYMPH; INSECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CARBOHYDRATE METABOLISM; CELL AGGREGATION; DNA PRIMERS; GLYCOSIDE HYDROLASES; GLYCOSYLATION; HEMOCYTES; IMMUNOGLOBULINS; INSECT PROTEINS; LECTINS; MICROSPHERES; MOTHS; PROTEINS; RECOMBINANT PROTEINS;

EID: 0000192633     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00934.x     Document Type: Article

References (35)

1. 1. Ratcliffe, N. (1993) Cellular defense responses of insects: unresolved problems. In: Parasites and Pathogens of Insects (Beckage, N., Thompson, S. & Federici, B., eds), pp. 267-298, Academic Press, San Diego.
2. 2. Faye, I. & Hultmark, D. (1993) The insect immune proteins and the organization and regulation of their genes. In Parasites and Pathogens of Insects (Beckage, N., Thompson, S.N. & Federici, B., eds), pp. 25-53. Academic Press, San Diego.
3. 3. Hoffmann, J. & Reichhart, J.-M. (1997) Drosophila immunity. Trends Cell Biol. 7, 309-316.
4. 4. Faye, I., Pye, A., Rasmusson, T., Boman, H.G. & Boman, I.A. (1975) Insect immunity II. Simultaneous induction of antibacterial activity and selective synthesis of some hemolymph proteins in diapausing pupae of Hyalophora cecropia and Samia cynthia. Infect. Immun. 12, 1426-1438.
5. 5. Rasmuson, T. & Boman, H.G. (1979) Insect immunity V. Purification and some properties of immune protein P4 from haemolymph of Hyalophora cecropia pupae. Insect Biochem. 9, 259-264.
6. 6. Andersson, K. & Steiner, H. (1987) Structure and properties of protein P4, the major bacteria-inducible protein in pupae of Hyalophora cecropia. Insect. Biochem. 17, 133-140.
7. 7. Lee, J.Y., Edlund, T., Ny, T., Faye, I. & Boman, H.G. (1983) Insect immunity. Isolation of cDNA clones corresponding to attacins and immune protein P4 from Hyalophora cecropia. EMBO J. 2, 577-581.
8. 8. Sun, S.-C, Lindström, I., Boman, H.G., Faye, I. & Schmidt, O. (1990) Hemolin: an insect immune protein belonging to the immunoglobulin superfamily. Science 250, 1729-1732.
9. 9. Schmidt, O., Faye, I., Lindström-Dinnetz, I. & Sun, S.-C. (1993) Specific immune recognition of insect hemolin. Dev. Comp. Immunol. 17, 195-200.
10. 10. Ladendorff, N.E. & Kanost, M.R. (1991) Bacteria induced protein P4 (hemolin) from Manduca sexta: a member of the immunoglobulin superfamily, which can inhibit hemocyte aggregation. Arch. Insect Biochem. Physiol. 18, 285-300.
11. 11. Ladendorff, N.E. & Kanost, M.R. (1990) Isolation and characterization of bacteria induced protein P4 from hemolymph of Manduca sexta. Arch. Insect Biochem. Physiol. 15, 33-41.
12. 12. Shin, S., Park, S.-S., Park, D.-S., Kim, M., Kim, S., Brey, P. & Park, H.-Y. (1998) Isolation and characterization of immune-related genes from the fall webworm, Hyphantria cunea, using PCR-based differential display and subtractive cloning. Insect Biochem. Mol, Biol. 28, 827-837.
13. 13. Faye, I. & Kanost, M. (1998) Function and regulation of hemolin. In: Molecular Mechanisms of Immune Responses in Insects (Brey, P.T. & Hultmark, D., eds). pp. 173-188. Chapman & Hall, London.
14. 14. Daffre, S. & Faye, I. (1997) Lipopolysaccharide interaction with hemolin, an insect member of the Ig-superfamily. FEBS Lett. 408, 127-130.
15. 15. Zhao, L. & Kanost, M.R. (1995) In search of a function for hemolin, a hemolymph protein from the immunoglobulin superfamily. J. Insect Physiol. 42, 73-79.
16. 16. Lanz-Mendoza, H., Bettencourt, R., Fabbri, M. & Faye, I. (1996) Regulation of the insect immune response: the effect of hemolin on cellular immune mechanisms. Cell. Immunol. 168, 47-54.
17. 17. Bettencourt, R., Lanz-Mendoza, H., Roxström-Lindquist, K. & Faye, I. (1997) Cell adhesion properties of hemolin, an insect immune protein in the Ig superfamily. Eur. J. Biochem. 250, 630-637.
18. 18. Lindström-Dinnetz, I., Sun, S.-C. & Faye, I. (1995) Structure and expression of hemolin, an insect member of the immunoglobulin gene superfamily. Eur. J. Biochem. 230, 920-925.
19. 19. Su, X.-D., Gastinel, L.N., Vaughn, D.E., Faye, I., Poon, P. & Bjorkman, P. (1998) Crystal structure of Hemolin: a horseshoe shape with implications for homophilic adhesion. Science 281, 991-995.
20. 20. Rader, C., Kunz, B., Lierheimer, R., Giger, R., Berger, P., Tittmann, P., Gross, H. & Sonderegger, P. (1996) Implications for the domain arrangement of axonin-1 derived from the mapping of its NgCAM binding site. EMBO J. 15, 2056-2968.
21. 21. Lanz-Mendoza, H. & Faye, I. (1999) Physiological aspects of the immunoglobulin superfamily in invertebrates. Dev. Comp. Immunol. 23, 359-374.
22. 22. Summers, M. & Smith, G. (1987) A manual of methods for baculovirus vectors and insect cell culture procedures. Tex. Agric. Exp. Stn. Bull. 1555, 1-56.
23. 23. Steiner, H., Pohl, G., Gunne, H., Hellers, M., Elhammer, Å. & Hansson, L. (1988) Human tissue-type plasminogen activator synthesized by using a baculovirus vector in insect cells compared with human plasminogen activator produced in mouse cells. Gene 73, 449-457.
24. 24. Towbin, H., Staehelin, T. & Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and applications. Proc. Natl Acad. Sci. USA 76, 4350-4354.
25. 45Ca autoradiography on nitrocellulose membrane after dodecyl sulfate gel electrophoresis. J. Biochem. 95, 511-519.
26. 26. Roth, J., Kempf, A., Reuter, G., Schauer, R. & Gehring, W. (1992) Occurence of sialic acids in Drosophila melanogaster. Science 256, 673-675.
27. 27. Sgroi, D., Nocks, A. & Stamenkovic, I. (1996) A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33. J. Biol. Chem. 271, 18803-18809.
28. 28. Kelm, S., Brossmer, R., Isecke, R., Gross, H.J., Strenge, K. & Schauer, R. (1998) Functional groups of sialic acids involved in binding to siglecs (sialoadhesions) deduced from interactions with synthetic analogues. Eur. J. Biochem. 255, 663-672.
29. 29. Kadmon, G., Kowitz, A., Altevogt, P. & Schachner, M. (1990) Functional cooperation between the neural adhesion molecule L1 and N-CAM is carbohydrate dependent. J. Cell Biol. 110, 209-218.
30. 30. Horstkorte, R., Schachner, M., Magyar, J.P., Vorherr, J. & Schmitz, B. (1993) The fourth immunoglobulin-like domain for NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth. J. Cell Biol. 121, 1409-1421.
31. 31. Feizi, J. (1994) Evidence for carbohydrate-mediated interactions between the neural cell adhesion molecules NCAM und L1. TIBS 19, 233-234.
32. 32. Maurer, P., Hohenester, E. & Engel, J. (1996) Extracellular calcium-binding proteins. Curr. Opin. Cell Biol. 8, 609-617.
33. 33. da Silva, A.C.R. & Reinach, F. C. (1991) Calcium binding induces conformational changes in muscle regulatory proteins. Trends Biochem. Sci. 16, 53-57.
34. 34. Bennet, M., Schlunegger, M. & Eisenberg, D. (1995) 3D Domain swapping: a mechanism for oligomeric assembly. Protein Sci. 4, 2455-2468.
35. 35. Tedder, T.F., Sleeber, D.A., Chen, A. & Engel, P. (1995) The Selectins: vascular adhesion molecules. FASEB J. 9, 866-873.