Simplified synthesis of the bifunctional chelating agent 2-(4-aminobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴- tetraacetic acid

New Journal of Chemistry

Volumn 20, Issue 5, 1996, Pages 585-588

  Mishra, A K ^a   Gestin, J F ^a   Benoist, E ^a   Faivre Chauvet, A ^a   Chatal, J F ^a  

^a INSERM   (France)

Author keywords

ABz DOTA; BCA; Bis( bromoamide); Nbz DOTA

Indexed keywords

EID: 0000094551     PISSN: 11440546     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

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16. A comparison of the number of steps and the total yield (%) for the synthesis of aminobenzyl-tetraazacyclododecane tetracetate from commercially available materials is as follows (see Scheme 1): present method, six steps with 21%; ref. 9, eight steps with 7.7%; ref. 10, six steps with 11.2%; ref. 11 (b), seven steps with 9.8%.