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2742531665
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note
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2+ moiety bound to the duplex and one with the same moiety free) in the form of doublings of H9 and HI protons (supporting information).
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0028126823
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2742544957
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BLM carries a 2,4′-bithiazole in its DNA-binding domain although the ring system is connected to positively-charged amine tails that results in stronger DNA binding
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BLM carries a 2,4′-bithiazole in its DNA-binding domain although the ring system is connected to positively-charged amine tails that results in stronger DNA binding.
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30
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85088230318
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15
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15
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31
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0025308014
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33
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85088226509
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note
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16 Clearly, the acridine ring of 6 intercalates into the base stack of 8 in a classical manner.
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34
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85088227722
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24
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24
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35
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2742554880
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note
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No doubling of peaks is observed when simpler analogues like 3-5 are added to 8. These complexes most possibly do not stay close to the helix for long time (rapid on-and-off situation), and hence the diastereomeric A-DNA and A-DNA complexes are not resolved in the NMR spectra of the analogue-DNA adducts.
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36
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33845185294
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Turro, N.J.5
Barton, J.K.6
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