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Volumn 2, Issue 3, 2000, Pages 243-245

Chemically sensitive high throughput parallel analysis of solid phase supported library members

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0000036363     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc990061x     Document Type: Article
Times cited : (63)

References (32)
  • 12
    • 85037516821 scopus 로고    scopus 로고
    • Czarnik, A. W., DeWitt, S. H., Eds.; American Chemical Society: Washington, DC
    • Shapiro, M. J.; Lin, M.; Yan, B. On-Resin Analysis in Combinatorial Chemistry; Czarnik, A. W., DeWitt, S. H., Eds.; American Chemical Society: Washington, DC, 1997; pp 123-151.
    • (1997) On-resin Analysis in Combinatorial Chemistry , pp. 123-151
    • Shapiro, M.J.1    Lin, M.2    Yan, B.3
  • 15
    • 85037511186 scopus 로고    scopus 로고
    • note
    • Here, the term "truly parallel" refers to the ability of the analytical technique to simultaneously collect information from multiple samples, as opposed to methods such as mapping, in which the final data set contains information from all members but was actually collected in a sequential manner.
  • 26
    • 85037514806 scopus 로고    scopus 로고
    • note
    • The beads were obtained from Advanced ChemTech and were all composed of 100-200 mesh Merrifield resin (1% DVB cross-linked) with a loading of 0.5-0.9 mmol/g. The supported ligands were as follows: Boc-Tyr(2-Br-Z). Boc-Val, Boc-Arg(Tos). and Boc-Pro.
  • 27
  • 31
    • 85037521275 scopus 로고    scopus 로고
    • note
    • The materials and reaction stoichiometry were identical to those in ref 28. The reaction was carried out at room temperature under continuous stirring. At several times during the reaction, a small portion of the beads was removed, washed with dimethyl formamide then methylene chloride, and dried under ambient conditions.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.