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Here, the term "truly parallel" refers to the ability of the analytical technique to simultaneously collect information from multiple samples, as opposed to methods such as mapping, in which the final data set contains information from all members but was actually collected in a sequential manner.
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The beads were obtained from Advanced ChemTech and were all composed of 100-200 mesh Merrifield resin (1% DVB cross-linked) with a loading of 0.5-0.9 mmol/g. The supported ligands were as follows: Boc-Tyr(2-Br-Z). Boc-Val, Boc-Arg(Tos). and Boc-Pro.
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The materials and reaction stoichiometry were identical to those in ref 28. The reaction was carried out at room temperature under continuous stirring. At several times during the reaction, a small portion of the beads was removed, washed with dimethyl formamide then methylene chloride, and dried under ambient conditions.
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