Synthesis of novel chiral diazole derivative ligands for the enantioselective addition of diethylzinc to benzaldehyde

Journal of Organic Chemistry

Volumn 61, Issue 25, 1996, Pages 8915-8920

  Kotsuki, Hiyoshizo ^a,b   Wakao, Masahiro ^a,b   Hayakawa, Hiroyuki ^a,b   Shimanouchi, Tomoyasu ^a,b   Shiro, Motoo ^a,b  

^a KOCHI UNIVERSITY   (Japan)

^b RIGAKU CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000015776     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961388c     Document Type: Article

References (77)

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74. PM3-optimized structures of the lowest energy conformations are shown. Calculations were performed by MOPAC '93 implemented in ANCHOR II, a molecular design system for SUN computers, developed by FUJITSU, Ltd., and Kureha Chemical Industry Co., Ltd., 1992. MOPAC 93: Stewart, J. J. P. Fujitsu, Ltd., Tokyo, Japan, 1993.
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76. Unfortunately, the 13C NMR signals of the pentafluorophenyl ring were too weak to observe.
77. Interestingly, the cyclohexane carbons were detected to be nonequivalent. Clearly, this may be indicative of an internal hydrogen bonding between hydroxyl and pyrazole nitrogen groups.